|
|
We are focused on studying genetic disorders of brain, nerve & muscle. Through better understanding of neurological disorders will come better diagnoses and treatments. |
|
ying-hui fu's & louis ptáček's |
|||
| laboratories of neurogenetics | |||
|
Migraine |
migraine Migraine headache affects approximately 10-20% of the population and places a huge cost on society in terms of pain suffering and work loss. People with migraine usually have a strong family history and may vary in frequency, intensity, duration, pattern of associated symptoms, and degree of disability. They are usually moderate to severe in intensity, and may be incapacitating. They are episodic in nature, with some patients experiencing one attack annually and others experiencing attacks several times a week Our Research It is clear that there are strong genetic factors involved in migraine, but the mode of inheritance still remains unclear. One rare form of migraine called familial hemiplegic migraine is transmitted as an autosomal dominant trait, but it is likely that multiple genes contribute to headache susceptibility in common migraine types. By studying families suffering from migraine headache, we hope to elucidate the complicated genetics of this disorder to gain insight into the biology of headache and to apply such understanding toward developing better therapies for patients. Our Laboratories Sometimes, symptoms caused by other medical conditions can mimic the effect of genetic mutations. In such cases, diagnosis and treatment of the condition is most effectively provided through traditional medical channels. Academic research laboratories such as ours do not usually provide these services; rather we are focused on genetic discoveries we hope will lead to defining these future diagnostic and treatment pathways. Study Status We are currently studying the genetic mutation(s) associated with this condition and are not collecting additional samples at this time. However, research directions change with every new discovery. If you would like to be considered for future research studies on Migraines, please contact the Clinical Coordinator listed below. What Does Study Participation Involve? 1. As an initial screening process, you will be asked to fill out a questionnaire describing your family disease history. This questionnaire is used to help researchers assess your medical condition. 2. If your condition appears to match the condition currently under study, you may be asked to submit additional information, including medical records and/or test results that will be used in the medical evaluation. 3. You will be asked to donate a blood sample (approximately 2-3 tablespoons) which we will use to isolate the DNA that we study. Contact Kristin Wong, Clinical Coordinator University of California San Francisco Department of Neurology, MC 2922 1550 Fourth St., Room 546 San Francisco, CA 94158-2324 USA Tel: +1.415.502.3976 Fax: +1.415.502.5641 Email: kristin.wong2@ucsf.edu |
||
|
Quick Links: For more information, please visit the following sites: Headache - Hope Through Research |
|||
|
circadian rhythm & sleep | episodic diseases | neurodegeneration |
|||
|
UCSF - Department of Neurology,
MC 2922 1550 Fourth St., Room 548 San Francisco, CA 94158-2324 USA tel: +1.415.502.5614 fax: +1.415.502.5641 |
|||
|
If you experience any difficulties with this site, please email our web developer. The University of California, San Francisco, CA 94143, +1.415.476.9000 Copyright © 2004-2006 The Regents of the University of California. All Rights Reserved. |
|||
